Alzheimer’s Disease and Dementia Research: Highlights From 2018 – Sources and Research

See the infographic and read the full article here.

January

  • Traumatic brain injury and the risk of dementia diagnosis: A nationwide cohort study

https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002496

February

  • BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions

http://jem.rupress.org/content/215/3/927

March

  • Use of antiepileptic drugs and dementia risk—An analysis of Finnish health register and German health insurance data

https://onlinelibrary.wiley.com/doi/abs/10.1111/jgs.15358

April

  • β-Amyloid accumulation in the human brain after one night of sleep deprivation

https://www.pnas.org/content/115/17/4483

May

  • Assessment of the mid-life demographic and lifestyle risk factors of dementia using data from the Framingham Heart Study Offspring Cohort

https://content.iospress.com/articles/journal-of-alzheimers-disease/jad170917

June

  • Learning impairments, memory deficits, and neuropathology in aged tau transgenic mice are dependent on leukotrienes biosynthesis: Role of the cdk5 kinase pathway

https://link.springer.com/article/10.1007%2Fs12035-018-1124-7

July

  • Inert and seed-competent tau monomers suggest structural origins of aggregation

https://elifesciences.org/articles/36584

August

  • Postsynaptic proteome of non-demented individuals with Alzheimer’s disease neuropathology

https://content.iospress.com/articles/journal-of-alzheimers-disease/jad180179

September

  • Discriminative accuracy of [18F]flortaucipir positron emission tomography for Alzheimer disease vs other neurodegenerative disorders

https://jamanetwork.com/journals/jama/article-abstract/2702872

October

  • Aortic stiffness is associated with increased risk of incident dementia in older adults

https://content.iospress.com/articles/journal-of-alzheimers-disease/jad180449

November

  • A deep learning model to predict a diagnosis of Alzheimer disease by using 18F-FDG PET of the brain

https://pubs.rsna.org/doi/10.1148/radiol.2018180958

December

  • Genetic data and cognitively defined late-onset Alzheimer’s disease subgroups

https://www.nature.com/articles/s41380-018-0298-8